Searchable abstracts of presentations at key conferences in endocrinology

ea0011p704 | Reproduction | ECE2006

Cardiopulmonary impairment in young women with polycystic ovary syndrome

Orio F , Giallauria F , Palomba S , Cascella T , De Lorenzo A , Lucci R , Manguso F , Vuolo L , Russo T , Lombardi G , Colao A , Vigorito C

The polycystic ovary syndrome (PCOS) is not only the first cause of female infertility but also a complex, endocrine, multifaceted disease with important health implications. PCOS is often associated to the metabolic syndrome, and insulin resistance represents the main characteristics for both these syndromes. The metabolic disturbances characteristic of insulin-resistant states have been linked to the role of mitochondrial function and in particular to the maximal oxygen cons...

ea0011p688 | Reproduction | ECE2006

Identification and functional study of a new FSH receptor gene mutation in women affected by polycystic ovary syndrome (PCOS)

Ferrarini E , Jr Orio F , Palomba S , Cascella T , Dimida A , di Biase S , Labella D , Agretti P , de Marco G , Gianetti E , Vitti P , Colao A , Lombardi G , Pucci E , Pinchera A , Tonacchera M

Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women, affecting up to 10% of women in reproductive age. The evidence of polycystic ovaries at ultrasonography has been recently considered as a further criteria to diagnose PCOS. In order to determine whether FSH receptor gene affects hormonal and/or metabolic parameters of PCOS women the presence of FSH receptor gene mutations was investigated. Forthy women aged between 18 and 40 years with poly...